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Background: Curcumin and vanillin are the two useful compounds in food and medicine. Bismuth nitrate pentahydrate is an economical and ecofriendly reagent.

Method: Bismuth nitrate pentahydrate impregnated montmorillonite KSF clay and curcumin were subjected to microwave irradiation.

Results: Microwave-induced bismuth nitrate-promoted synthesis of vanillin from curcumin has been accomplished in good yield under solvent-free condition. Twenty-five different reaction conditions have been studied to optimize the process.

Conclusion: The present procedure for the synthesis of vanillin may find useful application in the area of industrial process development.


© 2012 Bandyopadhyay and Banik; licensee Springer.

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Creative Commons Attribution 3.0 License
This work is licensed under a Creative Commons Attribution 3.0 License.

Publication Title

Organic and Medicinal Chemistry Letters



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Chemistry Commons



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