Microwave-Induced Stereocontrol of β-Lactam Formation with an N-Benzylidene-9,10-dihydrophenanthren-3-amine via Staudinger Cycloaddition
The synthesis of 3-substituted 4-phenyl-1-(9,10-dihydrophenanthren-3-yl)azetidin-2-ones was achieved following Staudinger cycloaddition under microwave-induced conditions. The stereoselectivity of β-lactam formation depended on the power level of the microwave irradiation used in the experiments.
Bandyopadhyay, Debasish, and Bimal K. Banik. "Microwave‐Induced Stereocontrol of β‐Lactam Formation with an N‐Benzylidene‐9, 10‐dihydrophenanthren‐3‐amine via Staudinger Cycloaddition." Helvetica Chimica Acta 93.2 (2010): 298-301. https://doi.org/10.1002/hlca.200900212
Helvetica Chimica Acta