Ultrasound assisted one-pot synthesis of benzo-fused indole-4, 9-dinones from 1,4-naphthoquinone and α-aminoacetals

Authors

Quang H. Luu
Jorge D. Guerra
Cecilio M. Castañeda
Manuel A. Martinez
Jong Saunders
Benjamin A. Garcia, The University of Texas Rio Grande Valley
Brenda V. Gonzales, The University of Texas Rio Grande Valley
Anushritha R. Aidunuthula, The University of Texas Rio Grande Valley
Shizue Mito, The University of Texas Rio Grande ValleyFollow

Document Type

Article

Publication Date

5-2016

Abstract

A one-pot synthesis of benzo[f]indole-4,9-diones from 1,4-naphthoquinone with α-aminoacetals has been developed. This method provides a straightforward synthesis of benzo[f]indole-4,9-diones via intramolecular nucleophilic attack of aminoquinones to aldehydes under mild reaction conditions. The detailed mechanism was also investigated.

Comments

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Recommended Citation

Luu, Q. H., Guerra, J. D., Castañeda, C. M., Martinez, M. A., Saunders, J., Garcia, B. A., Gonzales, B. V., Aidunuthula, A. R., & Mito, S. (2016). Ultrasound assisted one-pot synthesis of benzo-fused indole-4, 9-dinones from 1,4-naphthoquinone and α-aminoacetals. Tetrahedron letters, 57(21), 2253–2256. https://doi.org/10.1016/j.tetlet.2016.04.031

Publication Title

Tetrahedron Lett.

DOI

10.1016/j.tetlet.2016.04.031