In the present study, we aimed to produce mineralized-collagen by hydrothermal process. A simple method not depending on additional foreign chemicals has been employed to isolate the mineralized-collagen fibers from bovine waste. The process of extraction involves the use of hydrothermal method from available bovine bones. The structural and morphological properties of the collagen fibers were characterized by using scanning electron microscopy and transmission electron microscopy. These results indicated well received collagen fibers, having a diameter less than 1 μm and with established mineral content in the individual fibers. The X-ray diffraction showed the crystalline feature of the obtained nano-compounds. The thermo gravimetric analysis was used to differentiate between the collagen and mineral parts of obtained product. Overall, the results generously indicated production of well received collagen fibers from bovine bones.
Sheikh, Faheem A.; Kanjwal, M. A.; Macossay-Torres, Javier; Muhammad, Muneeb A.; Cantu, Travis; Chronakis, Ioannis S.; Barakat, N. A. M.; and Kim, Hak Yong, "Fabrication of Mineralized Collagen from Bovine Waste Materials by Hydrothermal Method as Promised Biomaterials" (2011). Chemistry Faculty Publications and Presentations. 78.
Journal of Biomaterials and Tissue Engineering