Posters
Academic Level (Author 1)
Medical Student
Academic Level (Author 2)
Faculty
Discipline/Specialty (Author 2)
Neuroscience
Discipline Track
Clinical Science
Abstract
Alzheimer’s disease is becoming more prevalent worldwide, leading to a growing demand to understand its risk factors and their impact on disease progression. Notably, Diabetes Mellitus has emerged as a significant risk factor to the development of Alzheimer’s disease, given its association with cognitive impairment. Due to its pathophysiology, Diabetes Mellitus could potentially contribute to the progression of Alzheimer’s disease. This study involved a detailed chart review of Hispanic patients diagnosed with Alzheimer’s disease within the past five years, some of whom also had a preexisting diagnosis of Diabetes Mellitus. This study formed two cohorts: Alzheimer patients without Diabetes Mellitus and Alzheimer Patients with Diabetes Mellitus. Physician notes were assessed and graded using the Global Deterioration Scale to quantify the disease progression in these patients. An unpaired t-test was employed to analyze the differences between the two cohorts. The results indicated a non-significant correlation between the presence of Diabetes Mellitus and the progression of Alzheimer’s disease. However, patients with both Alzheimer’s disease and Diabetes Mellitus had a higher average grade on the Global Deterioration Scale compared to those without Diabetes Mellitus, suggesting a trend towards more advanced disease progression in the former group. It is important to consider that the study’s limitations, such as a small sample size may affect the generalizability of these results. Future research with a larger sample size and diverse populations is necessary to further elucidate the relationship between Diabetes Mellitus and Alzheimer’s disease progression.
Presentation Type
Poster
Recommended Citation
Gonzalez Tovar, Maria Camila and Baker, Kelsey, "The Impact of Diabetes Mellitus on the Severity of Alzheimer’s Disease in Hispanics in the Rio Grande Valley" (2024). Research Colloquium. 51.
https://scholarworks.utrgv.edu/colloquium/2024/posters/51
Included in
The Impact of Diabetes Mellitus on the Severity of Alzheimer’s Disease in Hispanics in the Rio Grande Valley
Alzheimer’s disease is becoming more prevalent worldwide, leading to a growing demand to understand its risk factors and their impact on disease progression. Notably, Diabetes Mellitus has emerged as a significant risk factor to the development of Alzheimer’s disease, given its association with cognitive impairment. Due to its pathophysiology, Diabetes Mellitus could potentially contribute to the progression of Alzheimer’s disease. This study involved a detailed chart review of Hispanic patients diagnosed with Alzheimer’s disease within the past five years, some of whom also had a preexisting diagnosis of Diabetes Mellitus. This study formed two cohorts: Alzheimer patients without Diabetes Mellitus and Alzheimer Patients with Diabetes Mellitus. Physician notes were assessed and graded using the Global Deterioration Scale to quantify the disease progression in these patients. An unpaired t-test was employed to analyze the differences between the two cohorts. The results indicated a non-significant correlation between the presence of Diabetes Mellitus and the progression of Alzheimer’s disease. However, patients with both Alzheimer’s disease and Diabetes Mellitus had a higher average grade on the Global Deterioration Scale compared to those without Diabetes Mellitus, suggesting a trend towards more advanced disease progression in the former group. It is important to consider that the study’s limitations, such as a small sample size may affect the generalizability of these results. Future research with a larger sample size and diverse populations is necessary to further elucidate the relationship between Diabetes Mellitus and Alzheimer’s disease progression.