Talks
Presenting Author Academic/Professional Position
Stacy M. Sebastian
Academic Level (Author 1)
Medical Student
Discipline/Specialty (Author 1)
Internal Medicine
Discipline Track
Patient Care
Abstract Type
Research/Clinical
Abstract
The postoperative complications of surgical interventions to treat pancreatic cancer are a major cause of cancer-related morbidity and death. Identification of prognostic factors that may exist at the time of presentation can allow for early stratification of patients who face the greatest risk of developing these complications following surgical resection. Early consideration of high-risk patients can improve the prediction of disease-free survival for patients with pancreatic adenocarcinoma (PDAC) who undergo surgical resection. The goal of this retrospective study is to identify postoperative complications and risk factors that may affect disease-free survival after classic pancreaticoduodenectomy (CP) and pylorus-preserving pancreaticoduodenectomy (PPP), two variations of surgical resections that treat pancreatic head tumors. Patients who underwent either procedure for diagnosed PDAC from 2015 to 2020 were included in a retrospective study of a single center in a largely Hispanic population. Risk factors for investigation included AJCC tumor classification, tumor size and imaging characteristics at presentation, histological differentiation, presence of pre-operative biliary stenting, resection margins, and combined vascular resection at the time of operation. Univariate and multivariate analysis of these variables can reveal significant risk factors that indicate poor likelihood of disease-free survival following surgical resection of PDAC. During medical and surgical consultation, patients with similar profiles can be stratified to improve postoperative outcomes following pancreaticoduodenectomy.
Presentation Type
Talk
Recommended Citation
Sebastian, Stacy M.; Okanlawon, Adedayo O.; Fonseca Badillo, Giuiseppe; Nwoschua, Daniel; Abraham, Christian; and Chang, Chelsea, "Prognostic risk factors for postoperative complications in patients with pancreatic adenocarcinoma: a single center retrospective cohort study" (2025). Research Colloquium. 6.
https://scholarworks.utrgv.edu/colloquium/presentation/talks/6
Included in
Prognostic risk factors for postoperative complications in patients with pancreatic adenocarcinoma: a single center retrospective cohort study
The postoperative complications of surgical interventions to treat pancreatic cancer are a major cause of cancer-related morbidity and death. Identification of prognostic factors that may exist at the time of presentation can allow for early stratification of patients who face the greatest risk of developing these complications following surgical resection. Early consideration of high-risk patients can improve the prediction of disease-free survival for patients with pancreatic adenocarcinoma (PDAC) who undergo surgical resection. The goal of this retrospective study is to identify postoperative complications and risk factors that may affect disease-free survival after classic pancreaticoduodenectomy (CP) and pylorus-preserving pancreaticoduodenectomy (PPP), two variations of surgical resections that treat pancreatic head tumors. Patients who underwent either procedure for diagnosed PDAC from 2015 to 2020 were included in a retrospective study of a single center in a largely Hispanic population. Risk factors for investigation included AJCC tumor classification, tumor size and imaging characteristics at presentation, histological differentiation, presence of pre-operative biliary stenting, resection margins, and combined vascular resection at the time of operation. Univariate and multivariate analysis of these variables can reveal significant risk factors that indicate poor likelihood of disease-free survival following surgical resection of PDAC. During medical and surgical consultation, patients with similar profiles can be stratified to improve postoperative outcomes following pancreaticoduodenectomy.
