New Algorithms for Protein Structure Comparison and Protein Structure Prediction

Authors

Zaixin Lu, University of Texas-Pan American

Date of Award

7-2010

Document Type

Thesis

Degree Name

Master of Science (MS)

Department

Computer Science

First Advisor

Dr. Bin Fu

Second Advisor

Dr. Zhixiang Chen

Third Advisor

Dr. Robert Schweller

Abstract

Proteins show a great variety of 3D conformations, which can be used to infer their evolutionary relationship and to classify them into more general groups; therefore algorithms of protein structure alignment, protein similarity search and protein structure prediction are very helpful for protein biologists. We developed new algorithms for the problems in this field. The algorithms are tested with structures from the Protein Data Bank (PDB) and SCOP, a Structure Classification of Protein Database. The experimental results show that our tools are more efficient than some well known systems for finding similar protein structures and predicting protein structures.

Comments

Copyright 2010 Zaixin Lu. All Rights Reserved.

https://www.proquest.com/dissertations-theses/new-algorithms-protein-structure-comparison/docview/746817449/se-2

Granting Institution

University of Texas-Pan American