Date of Award
Master of Science (MS)
Dr. Luis A. Materon
Dr. Subramanian Dhandayuthapani
Dr. Mohammed Farooqui
Mycoplasma genitalium is a bacterium with no cell wall and the second smallest free-living organism. It is an intracellular parasite that causes urethritis in men and women. Symptoms of infection in women can be missed and include vaginal malodor and discharge, painful urination and sexual intercourse. M. genitalium infection is a serious, though preventable and treatable, infection. Recently, due its notable characteristics, many studies have revealed an enormous amount of genetic and structural information on this bacterium. Furthermore, many of its genes have been characterized. The uncovering of roles of genes involved in signal transduction via phosphorylation and dephosphorylation mechanisms have provided some clues into the regulation of protein activation both in M. genitalium and M. pneumoniae. This study aims to investigate the role of the MG207 gene in M. genitalium that encodes a serine/threonine protein phosphatase that is believed to regulate the dephosphorylation of proteins involved in cytadherence.
University of Texas-Pan American