I. Norbornene as Organocatalyst: Unusual: Amination II. Stereoselective Synthesis of 3, 4 Di-Substituted β-Lactams; Classical vs Microwave Method

Authors

Ravi Reddaboyna, University of Texas-Pan American

Date of Award

5-2013

Document Type

Thesis

Degree Name

Master of Science (MS)

Department

Chemistry

First Advisor

Dr. Bimal K. Banik

Second Advisor

Dr. Narayan G. Bhat

Third Advisor

Dr. Jose J. Gutierrez

Abstract

I. Amine functionality is important in the preparation of biologically active and industrially useful molecules. Many approaches to form C―N bonds provide access to fine chemical building blocks, pharmaceuticals, agrochemicals, and surfactants. Microwave irradiation is a highly recommended ecofriendly approach for the synthesis of medicinally important compounds. Organic catalysis is important segment in the field of organic chemistry, for the synthesis of many complex molecules by providing a number of advantages.

II. Cancer refers to a large group of diseases characterized by uncontrolled cell multiplication and the ability of these cells to enter other tissues and spread to other parts of the body. β-Lactams are antibiotics that have a β-lactam ring nucleus. Antibiotics are types of medications that destroy or slow down the growth of bacteria. The Staudinger [2+2] cycloaddition reaction is one of the most fundamental method for the synthesis of structurally diverse 2-azetidinone derivatives.

Comments

Copyright 2013 Ravi Reddaboyna. All Rights Reserved.

https://www.proquest.com/dissertations-theses/i-norbornene-as-organocatalyst-unusual-amination/docview/1412699364/se-2

Granting Institution

University of Texas-Pan American