Document Type
Article
Publication Date
11-1-2020
Abstract
This work studied the potential of centrifugal spinning for the production of fibrous materials based on poly(D,L-lactic acid) (PDLLA) and poly(3-hydroxybutyrate) (PHB) with hydroxyapatite nanoparticles (n-Hap). The influence of n-Hap concentration (5, 10, and 15 wt.%) and spinneret angular speed on the final fiber morphology were analyzed. Further experimental evaluations were implemented to determine the effect of n-Hap on the thermal and mechanical performance. The optimum parameters that show a balance among high yield production of homogeneous fibers with the smallest fiber average diameter were found to be at 5 wt.% of n-Hap processed at 7000 rpm for PDLLA, and 5, 10, and 15 wt.% of n-Hap at 6000 rpm for PHB. The thermal stability, for both systems, was not significantly affected. The mechanical performance of PHB systems was improved with the addition of n-Hap. Osteoblast cell viability tests depicted a favorable cell response on the PDLLA systems.
Recommended Citation
Padilla-Gainza, VM, Rodríguez-Tobías, H, Morales, G, et al. Centrifugally spun mats based on biopolyesters/hydroxyapatite and their potential as bone scaffolds. J Appl Polym Sci. 2021; 138:e50139. https://doi.org/10.1002/app.50139
Publication Title
J Appl Polym Sci
DOI
10.1002/app.50139
Comments
© 2020 Wiley Periodicals LLC.
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