Synthesis of Superparamagnetic Zinc Ferrite Encased Fluorapatite Nanoparticles and Its Cytotoxicity Effects on MG-63 Cells

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Zinc ferrite (ZnFe2O4) nanoparticles encased fluorapatite (FAP) nanorods was successfully synthesized through hydrothermal method for biomedical applications. TEM image revealed the formation of ZnFe2O4 nanoparticle encased FAP nanorods with average size of about 60 ± 40 nm. Both ZnFe2O4 and ZnFe2O4–FAP samples exhibited superparamagnetic nature at 300 K with saturation magnetization (Ms) of 28.41 and 4.13 emu/g, respectively. Further, the superparamagnetic property of the ZnFe2O4 was investigated using langevin function and average magnetic moment per particle was found to be 606 μB . ZnFe2O4–FAP nanorods exhibited enhanced colloidal stability when compared to ZnFe2O4 nanospheres. The cytotoxicity results confirmed the enhanced cell viability (86%) at 500 µg/mL of ZnFe2O4–FAP nanorods than that of ZnFe2O4 nanospheres (76%). The above results indicate that the ZnFe2O4–FAP nanorods can be considered as a potential candidate for biomedical applications.


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Journal of Cluster Science