The impact of Obesity Class in Obesity Hypoventilation Syndrome: An Overlooked Condition

Document Type


Publication Date

Fall 2020


Obesity hypoventilation syndrome (OHS) is a condition consisting of obesity and daytime hypoventilation and is typically considered a diagnosis of exclusion. Clinical manifestations of patients with OHS include a BMI greater than 30, sleep-disordered breathing, and daytime hypercapnia with PaCO2 values greater than 45. Studies demonstrate that patients with undiagnosed OHS experience a decreased quality of life, higher hospitalizations rates, and an increased risk of morbidity and mortality. Despite the consequences of undiagnosed and untreated OHS, this condition continues to be overlooked. Therefore, in this study, we aim to increase clinicians’ index of suspicion for diagnosing OHS to improve early recognition of the condition and help prevent misdiagnosis. In this study we found certain characteristics to be significant in the diagnosis of OHS/OSA. These characteristics based on the logistic regression model used include Obese group III (BMI >=40) p-value (0.0005), CI (2.5, 24.9); Obese group II (35<=BMI

Academic Level

medical student

Mentor/PI Department

Internal Medicine

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