Pancreatic ductal adenocarcinoma (PDAC) is a devastating malignancy, especially as there are no current reliable methods of screening. Recently literature reports a significant relationship with pancreatic ductal adenocarcinoma and diabetes mellitus (DM). The pathologic molecular mechanism is not completely understood but it may hold insights into the development of novel screening and treatment options. In our study we compiled a list of 74 proteins involved in the PDAC and DM pathway, with 47 showing increased expression levels and 11 with decreased expression levels. These proteins are currently undergoing further computational analysis to identify their pathway interactions.
Moreland, Russell H. III and Khan, Sheema, "Further Decoding the Molecular Relationship Between Pancreatic Adenocarcinoma and Diabetes Mellitus" (2022). MEDI 9331 Scholarly Activities Clinical Years. 57.
Immunology and Microbiology