The Promise of Predictive Biomarkers for Antipsychotic Efficacy: A Review of Peripheral microRNAs to Evaluate Schizophrenia Treatment Response

Authors

Ramu Vadukapuram, The University of Texas Rio Grande ValleyFollow
Chintan Trivedi
Kaushal Shah
Zeeshan Mansuri
Abhishek Reddy

Document Type

Article

Publication Date

4-2022

Abstract

With the ongoing evolution in genetics, recent evidence highlights the role of circulatory microRNA (miRNA) for schizophrenia. The objective of this article is to explore the role of blood/serum miRNA expression in schizophrenia management and to review the expression of different miRNAs before and after treatment with antipsychotics. miRNAs can help increase the accuracy of diagnosis, identify patients at risk of developing schizophrenia, and possibly predict drug response. The collective evidence from this review showed that several miRNAs are promising candidates for schizophrenia diagnosis, management, and prognosis.

Comments

© Copyright 2022 Physicians Postgraduate Press, Inc.

Recommended Citation

Vadukapuram, R., Trivedi, C., Shah, K., Mansuri, Z., & Reddy, A. (2022). The Promise of Predictive Biomarkers for Antipsychotic Efficacy: A Review of Peripheral microRNAs to Evaluate Schizophrenia Treatment Response. The primary care companion for CNS disorders, 24(2), 21nr03048. https://doi.org/10.4088/PCC.21nr03048

Publication Title

The Primary Care Companion for CNS Disorders

DOI

https://doi.org/10.4088/PCC.21nr03048

Academic Level

resident

Mentor/PI Department

Psychiatry