
School of Medicine Publications and Presentations
Document Type
Article
Publication Date
12-2023
Abstract
Objective
We evaluated the relationship among community socioeconomic factors (poverty, income, and education), gender, and outcomes in patients who underwent ascending aortic, root, and arch surgery.
Methods
For 2634 consecutive patients, we associated patients' ZIP codes with community socioeconomic factors. The composite adverse outcome comprised death, persistent neurological injury, and renal failure necessitating dialysis at discharge. Multivariable analysis and Kaplan–Meier survival curveswere used. Men and women from the full cohort and from the elective patients were propensity matched.
Results
Median follow-up was 3.6 years (interquartile range, 1.2-9.3). Men lived in areas characterized by less poverty (P = .03), higher household income (P = .01), and more education (P = .02) than women; likewise, in the elective cohort, all community socioeconomic factors favored men (P ≤ .009). Female gender predicted composite adverse outcome (P = .006). In the propensity-matched women and men (820 pairs), the composite adverse outcome rates were 14.2% and 11%, respectively (P = .06). In 583 propensity-matched pairs of elective patients, men had less composite adverse outcome (P = .02), operative mortality (P = .04), and renal (P = .02) and respiratory failure (P = .0006). The 5- and 10-year survivals for these men and women were 74.2% versus 71.4% and 50.2% versus 48.2%, respectively (P= .06). All community socioeconomic factors in both propensity-matched groups nonsignificantly favored men.
Conclusions
This study is among the first to examine the association among community socioeconomic factors, gender, and outcomes in patients who undergo proximal aortic surgery. Female gender predicted a composite adverse outcome. In the elective patients, most adverse outcomes were significantly less in men. In the propensity-matched patients, all community socioeconomic factors favored men, although not significantly. Larger studies with patient-level socioeconomic information are needed.
Recommended Citation
Preventza, O., Akpan-Smart, E., Simpson, K. K., Cornwell, L. D., Amarasekara, H., Green, S. Y., ... & Coselli, J. S. (2023). The intersection of community socioeconomic factors with gender on outcomes after thoracic aortic surgery. The Journal of Thoracic and Cardiovascular Surgery, 166(6), 1572-1582. https://doi.org/10.1016/j.jtcvs.2022.10.014
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Publication Title
The Journal of Thoracic and Cardiovascular Surgery
DOI
https://doi.org/10.1016/j.jtcvs.2022.10.014
Academic Level
medical student
Comments
http://creativecommons.org/licenses/by/4.0/