Schizophrenia in DiGeorge Syndrome: A Unique Case Report

Authors

Sukaina Rizvi
Ali M. Khan, The University of Texas Rio Grande Valley
Hina Saeed
Akeem M. Aribara
Alexis Carrington
Alexa Griffiths
Abdul Mohit

Document Type

Article

Publication Date

8-14-2018

Abstract

Herein we present the unique case of a 21-year-old African American woman who presented with psychotic features and the incidental finding of basal ganglia calcifications on computed tomography (CT) scan of the head. She was initially presumed to have Fahr’s syndrome in the context of idiopathic bilateral basal ganglia calcifications and psychotic features. Genetic testing performed revealed the deletion of 22q11.2, thus establishing the diagnosis of DiGeorge syndrome. This case highlights the importance of noticing subtle physical exam findings along with laboratory findings as this led to the diagnosis of DiGeorge syndrome for this patient. This case is unique in two aspects; first, the finding of basal ganglia calcification via CT of the brain in patients with DiGeorge syndrome has rarely been reported in the literature. Second, this case highlights the strong genetic predisposition for schizophrenia in patients with DiGeorge syndrome.

Comments

© Copyright 2018 Rizvi et al.

Recommended Citation

Rizvi, S., Khan, A. M., Saeed, H., Aribara, A. M., Carrington, A., Griffiths, A., & Mohit, A. (n.d.). Schizophrenia in DiGeorge Syndrome: A Unique Case Report. Cureus, 10(8). https://doi.org/10.7759/cureus.3142

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Publication Title

Cureus

DOI

10.7759/cureus.3142

Academic Level

resident

Mentor/PI Department

Psychiatry