Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment

Authors

Andrew Massey
Shabnam Malik, The University of Texas Rio Grande ValleyFollow
Mohammed Sikander, The University of Texas Rio Grande ValleyFollow
Kyle Doxtater, The University of Texas Rio Grande Valley
Manish Tripathi, The University of Texas Rio Grande Valley
Sheema Khan, The University of Texas Rio Grande Valley
Murali M. Yallapu, The University of Texas Rio Grande ValleyFollow
Meena Jaggi, The University of Texas Rio Grande ValleyFollow
Subhash C. Chauhan, The University of Texas Rio Grande ValleyFollow
Bilal B. Hafeez, The University of Texas Rio Grande ValleyFollow

Document Type

Article

Publication Date

5-17-2021

Abstract

Exosomes are nanoscale vesicles generated by cells for intercellular communication. Due to their composition, significant research has been conducted to transform these particles into specific delivery systems for various disease states. In this review, we discuss the common isolation and loading methods of exosomes, some of the major roles of exosomes in the tumor microenvironment, as well as discuss recent applications of exosomes as drug delivery vessels and the resulting clinical implications

Comments

© 2021 by the authors.

Recommended Citation

Massey, A. E., Malik, S., Sikander, M., Doxtater, K. A., Tripathi, M. K., Khan, S., Yallapu, M. M., Jaggi, M., Chauhan, S. C., & Hafeez, B. B. (2021). Clinical Implications of Exosomes: Targeted Drug Delivery for Cancer Treatment. International journal of molecular sciences, 22(10), 5278. https://doi.org/10.3390/ijms22105278

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Publication Title

International Journal of Molecular Science

DOI

10.3390/ijms22105278

Academic Level

faculty

Mentor/PI Department

Immunology and Microbiology