School of Medicine Publications and Presentations

Document Type

Article

Publication Date

8-2017

Abstract

Magnetic nanoparticles (MNPs) play a vital role for improved imaging applications. Recently, a number of studies demonstrate MNPs can be applied for targeted delivery, sustained release of therapeutics, and hyperthermia. Based on stable particle size and shape, biocompatibility, and inherent contrast enhancement characteristics, MNPs have been encouraged for pre-clinical studies and human use. As a theranostic platform development, MNPs need to balance both delivery and imaging aspects. Thus, this review provides significant insight and advances in the theranostic role of MNPs through the documentation of unique magnetic nanoparticles used in prostate cancer, their interaction with prostate cancer cells, in vivo fate, targeting, and biodistribution. Specific and custom-made applications of various novel nanoformulations in prostate cancer are discussed.

Comments

Original published version available at 10.1016/j.drudis.2017.04.018

Publication Title

Drug Discovery Today

DOI

10.1016/j.drudis.2017.04.018

Academic Level

faculty

Mentor/PI Department

Immunology and Microbiology

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