Acute Lower Extremity Posterior Compartment Syndrome: A Rare Complication of Apixaban Use

Authors

Jennifer Adams, The University of Texas Rio Grande ValleyFollow
Jose H. Ramos, The University of Texas Rio Grande Valley
Shyama Appareddy M.D., The University of Texas Rio Grande Valley
Hoang Anh Thi Nguyen, The University of Texas Rio Grande Valley
Gustavo Garcia, The University of Texas Rio Grande Valley

Document Type

Article

Publication Date

4-15-2022

Abstract

Apixaban is an oral anticoagulant that directly inhibits Factor Xa and is indicated for the prophylaxis and treatment of deep venous thrombosis and stroke prevention in non-valvular atrial fibrillation. Acute lower extremity Posterior Compartment Syndrome is a rare complication of Apixaban use. We present a 78-year-old male with significant medical morbidities taking Apixaban for Atrial Fibrillation presenting with post-traumatic extensive hemorrhagic bullae on the left proximal pretibial region secondary to anticoagulation. We recommend that clinicians develop awareness of the potential for serious bleeding complications of anticoagulants and devise strategies to identify the need for early recognition and prompt management.

Comments

© 2022 Adams J, et al.

Recommended Citation

Adams J, Ramos JH, Appareddy S, et al. Acute lower-extremity posterior compartment syndrome: a rare complication of apixaban use. AIM Clinical Cases. 2022;1:e220290. doi:10.7326/aimcc.2022.0290

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.

Publication Title

Annals of Internal Medicine Clinical Cases

DOI

10.7326/aimcc.2022.0290

Academic Level

faculty

Mentor/PI Department

Internal Medicine