School of Medicine Publications and Presentations
Document Type
Article
Publication Date
7-18-2019
Abstract
AIM
To evaluate the light adjustable lens (LAL) vs a standard monofocal lens in achieving target astigmatic refraction and improving postoperative uncorrected distance visual acuity (UDVA).
METHODS
This randomized controlled clinical trial included 40 patients with pre-existing astigmatism and visually significant cataract. Twenty-eight patients received the LAL and 12 control patients received a monofocal intraocular lens (IOL) after cataract extraction at a single institution. The patients with the LAL underwent adjustment by ultraviolet (UV) light postoperatively plus subsequent lock-in procedures and all patients returned to clinic for follow up of study parameters at 6, 9, and 12mo. Manifest refraction, distance visual acuity, and adverse events were recorded at each visit.
RESULTS
The mean cylinder before adjustment in eyes with the LAL was -0.89±0.58 D (-2.00 to 0.00 D) and -0.34±0.34 D (-1.25 to 0.00 D) after lock-in (P=1.68x10−8). The mean cylinder in patients with the monofocal lens was -1.00±0.32 D (-1.50 to -0.50 D) at 17-21d postoperatively, which was statistically different from the LAL cylinder post lock-in (P=1.43x10−6). UDVA in the LAL group was 20/20 or better in 79% of patients post lock-in with good stability over 12mo compared with 33% of the control patients with UDVA of 20/20 or better.
CONCLUSION
These results demonstrate that the LAL is more effective in achieving target refractions and improving postoperative UDVA in patients with pre-existing corneal astigmatism than a standard monofocal lens.
Recommended Citation
Moshirfar, M., Wagner, W. D., Linn, S. H., Skanchy, D. F., Brown, T. W., Gomez, A. T., Goldberg, J. L., Ronquillo, Y. C., & Hoopes, P. C., Jr (2019). Astigmatic correction with implantation of a light adjustable vs monofocal lens: a single site analysis of a randomized controlled trial. International journal of ophthalmology, 12(7), 1101–1107. https://doi.org/10.18240/ijo.2019.07.08
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Publication Title
Int J Ophthalmol
DOI
10.18240/ijo.2019.07.08
Academic Level
medical student
Comments
Copyright International Journal of Ophthalmology Press IJO Press applies the Creative Commons Attribution (CC BY NC ND) license to works we publish.