School of Medicine Publications and Presentations

Impact of Paternal Depression on Child Neurodevelopmental Outcomes and Disorders

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Objective: To explore paternal depression (before, during, and after pregnancy) and its association with neurodevelopmental disorders in children.

Data Sources: A systematic, English-language review was conducted in PubMed, PubMed Central, MEDLINE, Web of Science, BIOSIS Previews, and SciELO. All relevant literature published from inception to March 31, 2021, was included. The MeSH terms used in the search included paternal behavior, fathers, or father-child relations in the context of depression, postpartum depression, and neurodevelopmental disorders.

Data Extraction: The PICOS (Population, Intervention, Comparison, Outcomes, and Study design) tool was used to enhance reporting of the findings. Twenty-six articles were included in the review.

Results: Paternal depression during the perinatal period resembles maternal perinatal depression. Early paternal depression has considerable emotional, behavioral, and developmental impacts on their children. Genetic endowment and environmental factors induced by paternal depression-related behaviors may lead to adverse neurodevelopmental outcomes.

Conclusions and Relevance: The findings suggest that paternal depression negatively influences neurodevelopmental disorders in the offspring.


© 2023 Physicians Postgraduate Press, Inc.

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Primary Care Companion for CNS Disorders



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