Posters
Presenting Author Academic/Professional Position
Medical Student
Academic Level (Author 1)
Medical Student
Academic Level (Author 2)
Medical Student
Academic Level (Author 3)
Faculty
Discipline/Specialty (Author 3)
Internal Medicine
Academic Level (Author 4)
Resident
Academic Level (Author 5)
Resident
Presentation Type
Poster
Discipline Track
Clinical Science
Abstract Type
Research/Clinical
Abstract
As the prevalence of diabetes continues to rise in the United States, affecting a significant portion of the population, it is critical to explore its potential connections with other prevalent conditions like psoriasis, as this may influence treatment approaches for diabetes patients in general. This literature review examines the relationship between psoriasis and Type 2 Diabetes Mellitus (T2DM), focusing on how these conditions might be interrelated, which is vital for developing comprehensive management strategies that consider both dermatological and metabolic aspects.
Recent studies have shown a strong relationship between psoriasis, metabolic disorders, and Type 2 Diabetes Mellitus (T2DM). However, the exact causal mechanism linking psoriasis and T2DM remains unclear. Some studies suggest that chronic inflammation, mediated by TNF-α and other pro-inflammatory cytokines such as IL-1 and IL-6, may contribute to both conditions, leading to endothelial dysfunction, altered glucose metabolism, insulin resistance, and hyperkeratosis.
On the other hand, recent research has indicated no direct association between psoriasis and diabetes, suggesting instead that they share common comorbidities such as obesity and smoking.
This literature review aims to examine large-scale studies claiming a direct association between psoriasis and diabetes and evaluate whether these studies have accounted for the influence of shared comorbidity BMI and reassess the validity of the studies’ conclusions.
Recommended Citation
Woo, Jihoo; Wiggins, Russell; Chang, Chelsea; Tran, Victor; Morales, Elimar; Elizondo, Ramon; and Cauba, John N., "Exploring the Association Between Psoriasis and Type 2 Diabetes Mellitus: A Literature Review" (2025). Research Symposium. 74.
https://scholarworks.utrgv.edu/somrs/2025/posters/74
Included in
Exploring the Association Between Psoriasis and Type 2 Diabetes Mellitus: A Literature Review
As the prevalence of diabetes continues to rise in the United States, affecting a significant portion of the population, it is critical to explore its potential connections with other prevalent conditions like psoriasis, as this may influence treatment approaches for diabetes patients in general. This literature review examines the relationship between psoriasis and Type 2 Diabetes Mellitus (T2DM), focusing on how these conditions might be interrelated, which is vital for developing comprehensive management strategies that consider both dermatological and metabolic aspects.
Recent studies have shown a strong relationship between psoriasis, metabolic disorders, and Type 2 Diabetes Mellitus (T2DM). However, the exact causal mechanism linking psoriasis and T2DM remains unclear. Some studies suggest that chronic inflammation, mediated by TNF-α and other pro-inflammatory cytokines such as IL-1 and IL-6, may contribute to both conditions, leading to endothelial dysfunction, altered glucose metabolism, insulin resistance, and hyperkeratosis.
On the other hand, recent research has indicated no direct association between psoriasis and diabetes, suggesting instead that they share common comorbidities such as obesity and smoking.
This literature review aims to examine large-scale studies claiming a direct association between psoriasis and diabetes and evaluate whether these studies have accounted for the influence of shared comorbidity BMI and reassess the validity of the studies’ conclusions.
