Posters
Academic Level (Author 1)
Staff
Discipline/Specialty (Author 1)
Neuroscience
Academic Level (Author 2)
Faculty
Discipline/Specialty (Author 2)
Human Genetics
Discipline Track
Translational Science
Abstract
Introduction: The Brazilian short-tailed opossum (Monodelphis Domestica) is an understudied animal model compared to the Mus musculus that has been identified as a perfect candidate to study neurodevelopment (Baggott, L. & Moore, H., 1990). What makes the Monodelphis Domestica a perfect specimen for neurodevelopment is that the embryo develops outside the pouch of the mother providing easy noninvasive access to track changes across different developmental stages (Mate et al., 1994).
Objective: The objective of the study is to compare the area and volume in the development of the Monodelphis’s midbrain across three different developmental stages. Our research is beneficial because it facilitates the study of neurodevelopmental mental health disorders and its impact in the brain.
Methods: We utilized ImageJ and Zen software to perform the volumetric and area analysis of these stages. To conduct a volumetric analysis a Volume Macro code was used in ImageJ software. The area analysis was completed using Zen software. A descriptive analysis was used to compare the differences in area and volume across the developmental stages.
Presentation Type
Poster
Recommended Citation
Perez, Ismael; VandeBerg, John L.; and Gil, Mario, "A preliminary timeline of the midbrain development in the Monodelphis Domestica animal model" (2023). Research Colloquium. 28.
https://scholarworks.utrgv.edu/colloquium/presentation/poster/28
A preliminary timeline of the midbrain development in the Monodelphis Domestica animal model
Introduction: The Brazilian short-tailed opossum (Monodelphis Domestica) is an understudied animal model compared to the Mus musculus that has been identified as a perfect candidate to study neurodevelopment (Baggott, L. & Moore, H., 1990). What makes the Monodelphis Domestica a perfect specimen for neurodevelopment is that the embryo develops outside the pouch of the mother providing easy noninvasive access to track changes across different developmental stages (Mate et al., 1994).
Objective: The objective of the study is to compare the area and volume in the development of the Monodelphis’s midbrain across three different developmental stages. Our research is beneficial because it facilitates the study of neurodevelopmental mental health disorders and its impact in the brain.
Methods: We utilized ImageJ and Zen software to perform the volumetric and area analysis of these stages. To conduct a volumetric analysis a Volume Macro code was used in ImageJ software. The area analysis was completed using Zen software. A descriptive analysis was used to compare the differences in area and volume across the developmental stages.