Posters
Academic Level (Author 1)
Staff
Discipline/Specialty (Author 1)
Neuroscience
Academic Level (Author 2)
Faculty
Discipline/Specialty (Author 2)
Human Genetics
Discipline Track
Biomedical Science
Abstract
Mus Musculus is one of the first and widely used animal models in neuroscience. There are many reasons that Mus Musculus is used for research including, short generation length and large litters, but the most important reason is their mammalian brain. Another animal that is gaining interest as an animal model is the Monodelphis Domestica. The Monodelphis Domestica is a marsupial, pups are born underdeveloped and move onto the underbelly of their mothers until they reach a more mature age. One difference is the Monodelphis ventricle size is much larger in the forebrain area. Another difference is the formation of the corpus callosum. In the mouse brain, the corpus callosum forms and fuses before the hippocampus compared to the possum where the corpus callosum is formed more posterior to the formation of the hippocampus. The corpus callosum of the Monodelphis is less prominent than the anterior commissure. In the mouse brain, the majority of the nerve fibers are found in the corpus callosum as opposed to the anterior commissure. The corpus callosum allows communication between both hemispheres of the brain. In the mus musculus, the hippocampus is well defined and begins formation after the formation of the corpus callosum. In the Monodelphis, the hippocampus is not as defined. The mus musculus is a social animal, the more defined hippocampus could be an evolutionary improvement for social interaction. The Monodelphis is a more territorial and isolated species. Looking at the differences between the two, can further knowledge into the behavioral differences.
Presentation Type
Poster
Recommended Citation
Botello, Cristian M.; VandeBerg, John L.; and Gil, Mario, "A Neural Comparison Between Mus Musculus and Monodelphis Domestica" (2023). Research Colloquium. 29.
https://scholarworks.utrgv.edu/colloquium/presentation/poster/29
Included in
A Neural Comparison Between Mus Musculus and Monodelphis Domestica
Mus Musculus is one of the first and widely used animal models in neuroscience. There are many reasons that Mus Musculus is used for research including, short generation length and large litters, but the most important reason is their mammalian brain. Another animal that is gaining interest as an animal model is the Monodelphis Domestica. The Monodelphis Domestica is a marsupial, pups are born underdeveloped and move onto the underbelly of their mothers until they reach a more mature age. One difference is the Monodelphis ventricle size is much larger in the forebrain area. Another difference is the formation of the corpus callosum. In the mouse brain, the corpus callosum forms and fuses before the hippocampus compared to the possum where the corpus callosum is formed more posterior to the formation of the hippocampus. The corpus callosum of the Monodelphis is less prominent than the anterior commissure. In the mouse brain, the majority of the nerve fibers are found in the corpus callosum as opposed to the anterior commissure. The corpus callosum allows communication between both hemispheres of the brain. In the mus musculus, the hippocampus is well defined and begins formation after the formation of the corpus callosum. In the Monodelphis, the hippocampus is not as defined. The mus musculus is a social animal, the more defined hippocampus could be an evolutionary improvement for social interaction. The Monodelphis is a more territorial and isolated species. Looking at the differences between the two, can further knowledge into the behavioral differences.