Talks
Presentation Type
Oral Presentation
Discipline Track
Clinical Science
Abstract Type
Case Report
Abstract
Background: The Coronavirus disease 2019 (COVID-19) pandemic is predicted to have a net negative effect on tuberculosis (TB) control, with an estimated excess of 6.3 million tuberculosis cases and 1.4 million deaths by 2025. Programmatic issues like the lockdown of TB services affect all patients, while biosocial factors have a differential impact on an individual’s risk for TB or adverse TB outcomes.
Case presentation: We report three cases of incident TB after resolution of COVID-19 episodes.Coincidently, all cases shared a common risk factor: a chronic history poorly-controlled diabetes.
Conclusions: Our findings alert to the threat posed by the synergy between COVID-19 and diabetes, on TB reactivation. In medium- to high-risk settings for TB, we recommend implementation of routine screening for latent TB infection in these cases, and preventive TB treatment in those who are positive.
Published version of this presentation: Aguillón-Durán, G.P., Prieto-Martínez, E., Ayala, D. et al. COVID-19 and chronic diabetes: the perfect storm for reactivation tuberculosis?: a case series. J Med Case Reports 15, 621 (2021). https://doi.org/10.1186/s13256-021-03193-7
Academic/Professional Position
Faculty
Mentor/PI Department
Office of Human Genetics
Recommended Citation
Aguillón-Durán, Genesis P.; Prieto-Martinez, Ericka; Ayala, Doris; Garcia, Juan Jr; Thomas, John M.; Garcia, Juan I.; Torrelles, Jordi B.; Ledezma-Campos, Eder; and Restrepo, Blanca I., "COVID-19 and chronic diabetes: The perfect storm for reactivation TB?" (2023). Research Symposium. 7.
https://scholarworks.utrgv.edu/somrs/theme1/track1/7
Included in
Bacterial Infections and Mycoses Commons, Endocrine System Diseases Commons, Virus Diseases Commons
COVID-19 and chronic diabetes: The perfect storm for reactivation TB?
Background: The Coronavirus disease 2019 (COVID-19) pandemic is predicted to have a net negative effect on tuberculosis (TB) control, with an estimated excess of 6.3 million tuberculosis cases and 1.4 million deaths by 2025. Programmatic issues like the lockdown of TB services affect all patients, while biosocial factors have a differential impact on an individual’s risk for TB or adverse TB outcomes.
Case presentation: We report three cases of incident TB after resolution of COVID-19 episodes.Coincidently, all cases shared a common risk factor: a chronic history poorly-controlled diabetes.
Conclusions: Our findings alert to the threat posed by the synergy between COVID-19 and diabetes, on TB reactivation. In medium- to high-risk settings for TB, we recommend implementation of routine screening for latent TB infection in these cases, and preventive TB treatment in those who are positive.
Published version of this presentation: Aguillón-Durán, G.P., Prieto-Martínez, E., Ayala, D. et al. COVID-19 and chronic diabetes: the perfect storm for reactivation tuberculosis?: a case series. J Med Case Reports 15, 621 (2021). https://doi.org/10.1186/s13256-021-03193-7