Key Enzymes in Cancer: Mechanism of Action and Inhibition With Anticancer Agents

Authors

Debasish Bandyopadhyay, The University of Texas Rio Grande ValleyFollow
Gabriel Lopez, The University of Texas Rio Grande Valley
Stephanie Cantu, The University of Texas Rio Grande Valley
Samantha Balboa, The University of Texas Rio Grande Valley
Annabel Garcia, The University of Texas Rio Grande Valley
Christina Silva, The University of Texas Rio Grande Valley
Diandra Valdes, The University of Texas Rio Grande Valley

Document Type

Book

Publication Date

2018

Abstract

Several enzymes play significant role in different stages of cancer including proliferation, invasion, metastasis and angiogenesis. Mechanism of actions of a few key enzymes along with their inhibitors have been discussed with particular attentation to riboneucleotide reductase, thymidylate synthease, topoisomerase II, interleukins, cell survival proteins and aminopeptidase N.

Comments

© 2004 - 2021 Nova Science Publishers | All Rights Reserved.

Recommended Citation

Debasish Bandyopadhyay, Gabriel Lopez, Stephanie Cantu, Samantha Balboa, Annabel Garcia, Christina Silva, Diandra Valdes. In Chemistry Research and Applications (Vol. 2): Organic and Medicinal Chemistry, Chapter 9; Key Enzymes in Cancer: Mechanism of Action and Inhibition with Anticancer Agents. 2018, Nova Science Publishers, Inc., Hauppauge, New York, USA (ISBN: 978-1-53614-855-8).

Publication Title

Chemistry Research and Applications (Vol. 2): Organic and Medicinal Chemistry