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Internal Medicine

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Case Report

Abstract

Doxycycline is a commonly used antibiotic, but rarely, it can induce pseudotumor cerebri (PTC), a condition marked by increased intracranial pressure without a mass lesion. We report a case of a 35-year-old woman with diabetes and stage 4 chronic kidney disease who developed headache and blurry vision two weeks after completing doxycycline for H. pylori. Imaging was unremarkable, but lumbar puncture showed elevated opening pressure (40 cm H₂O) with normal CSF, confirming PTC. The patient improved with acetazolamide and was asymptomatic on follow-up. This case underscores the need for clinicians to consider doxycycline-induced PTC in patients presenting with visual changes or headaches after antibiotic therapy.

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Doxycycline-Associated Intracranial Hypertension in the Treatment of H. pylori Infection: A case report

Doxycycline is a commonly used antibiotic, but rarely, it can induce pseudotumor cerebri (PTC), a condition marked by increased intracranial pressure without a mass lesion. We report a case of a 35-year-old woman with diabetes and stage 4 chronic kidney disease who developed headache and blurry vision two weeks after completing doxycycline for H. pylori. Imaging was unremarkable, but lumbar puncture showed elevated opening pressure (40 cm H₂O) with normal CSF, confirming PTC. The patient improved with acetazolamide and was asymptomatic on follow-up. This case underscores the need for clinicians to consider doxycycline-induced PTC in patients presenting with visual changes or headaches after antibiotic therapy.

 

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