Posters
Presenting Author Academic/Professional Position
Lois Faith Baldado
Academic Level (Author 1)
Medical Student
Academic Level (Author 2)
Medical Student
Academic Level (Author 3)
Faculty
Discipline/Specialty (Author 3)
Pharmacology
Discipline Track
Clinical Science
Abstract Type
Research/Clinical
Abstract
Background: Cervical cancer ranks 4th as the most prevalent cancer among women worldwide [1]. Within the United States, it is the third most common gynecological cancer [2]. Hispanic females had the highest incidence rate of cervical carcinoma between 2001 to 2018 [3]. Between 2017 and 2021, the incidence rate of cervical cancer in Hispanic females was 36% higher compared to White females [4].
The purpose of this retrospective study is to screen for a potential association between state residence in Texas, California, and New York and the acquisition of cervical cancer treatments among Hispanic women. We hypothesized there is a significant association between state residency and receiving cervical cancer treatments in Hispanic women due to sociopolitical factors such as insurance coverage, state laws, education level, and healthcare resources.
Methods: An IRB approval was received in May 2025 for the retrospective study of cancer data found in the National Cancer Institute SEER Program. We evaluated 28,658 de-identified cases in the Incidence – SEER Research Plus Limited-Field Data, 21 Registries (excl IL), Nov 2024 Sub (2000-2022) Database. The inclusion criteria were Hispanic (all races), female cervical cancer patients in Texas, New York, and California. Frequency statistics sessions on the SEER*Stat software version 9.0.40.1 were utilized to obtain matrices. Treatments of interest were chemotherapy, radiation-surgery sequence, and systemic treatment-surgery sequence; files were transferred from SEER to Excel to IBM SPSS.
Three separate IBM SPSS Chi-Square analyses were conducted to test for significance for the three treatment categories. We combined all radiation-surgery sequences into two categories for Phi-Cramer’s V chi square analyses (ex: none received/unknown vs. radiation and/or surgery received regardless of sequence). The same method was applied for the systemic treatment-surgery sequences analyses. Blank cases from SEER were labeled as “missing data” on IBM SPSS for exclusion from all three statistical analyses.
Results: All three Chi-Square analyses displayed significant associations between state residency (TX, CA, NY) and chemotherapy status, radiation-surgery sequence, and systemic treatment-surgery sequences among Hispanic, female cervical cancer patients. Pearson-Chi Square values for the three analyses were all < 0.001, significantly lower than our chosen alpha value of p = 0.05. The likelihood ratio for the Surgical Radiation Chi-Square analyses was also < 0.001.
Conclusions: Reflecting on the statistical analyses of SEER cancer data, the results support our initial hypothesis that there is a significant association between state residence in these three states and the attainment of cervical cancer treatments among Hispanic patients. Further studies should assess how statewide Medicare coverage, immigration status, HPV vaccine status, income, education, and other socioeconomic factors impact cervical cancer treatment in Hispanic women.
Presentation Type
Poster
Recommended Citation
Baldado, Lois F.; De Hoyos, Learsi R.; and Mito, Shizue, "Significant Association Discovered Between State of Residence and the Acquisition of Cervical Cancer Therapies Among Hispanics in Texas, California, and New York" (2025). Research Colloquium. 60.
https://scholarworks.utrgv.edu/colloquium/2025/posters/60
Included in
Significant Association Discovered Between State of Residence and the Acquisition of Cervical Cancer Therapies Among Hispanics in Texas, California, and New York
Background: Cervical cancer ranks 4th as the most prevalent cancer among women worldwide [1]. Within the United States, it is the third most common gynecological cancer [2]. Hispanic females had the highest incidence rate of cervical carcinoma between 2001 to 2018 [3]. Between 2017 and 2021, the incidence rate of cervical cancer in Hispanic females was 36% higher compared to White females [4].
The purpose of this retrospective study is to screen for a potential association between state residence in Texas, California, and New York and the acquisition of cervical cancer treatments among Hispanic women. We hypothesized there is a significant association between state residency and receiving cervical cancer treatments in Hispanic women due to sociopolitical factors such as insurance coverage, state laws, education level, and healthcare resources.
Methods: An IRB approval was received in May 2025 for the retrospective study of cancer data found in the National Cancer Institute SEER Program. We evaluated 28,658 de-identified cases in the Incidence – SEER Research Plus Limited-Field Data, 21 Registries (excl IL), Nov 2024 Sub (2000-2022) Database. The inclusion criteria were Hispanic (all races), female cervical cancer patients in Texas, New York, and California. Frequency statistics sessions on the SEER*Stat software version 9.0.40.1 were utilized to obtain matrices. Treatments of interest were chemotherapy, radiation-surgery sequence, and systemic treatment-surgery sequence; files were transferred from SEER to Excel to IBM SPSS.
Three separate IBM SPSS Chi-Square analyses were conducted to test for significance for the three treatment categories. We combined all radiation-surgery sequences into two categories for Phi-Cramer’s V chi square analyses (ex: none received/unknown vs. radiation and/or surgery received regardless of sequence). The same method was applied for the systemic treatment-surgery sequences analyses. Blank cases from SEER were labeled as “missing data” on IBM SPSS for exclusion from all three statistical analyses.
Results: All three Chi-Square analyses displayed significant associations between state residency (TX, CA, NY) and chemotherapy status, radiation-surgery sequence, and systemic treatment-surgery sequences among Hispanic, female cervical cancer patients. Pearson-Chi Square values for the three analyses were all < 0.001, significantly lower than our chosen alpha value of p = 0.05. The likelihood ratio for the Surgical Radiation Chi-Square analyses was also < 0.001.
Conclusions: Reflecting on the statistical analyses of SEER cancer data, the results support our initial hypothesis that there is a significant association between state residence in these three states and the attainment of cervical cancer treatments among Hispanic patients. Further studies should assess how statewide Medicare coverage, immigration status, HPV vaccine status, income, education, and other socioeconomic factors impact cervical cancer treatment in Hispanic women.
