Posters

Academic Level (Author 1)

Medical Student

Discipline/Specialty (Author 1)

Neurology

Discipline Track

Patient Care

Abstract

Introduction: Uncontrolled blood glucose is notorious for inflicting multi-organ pathologies. One such pathology, chorea-hemiballism, has been reported in individuals who exhibited either hyperglycemia or hypoglycemia, and although rare, it is debilitating and calls for active management.

Case Description: A 50-year-old female, with a past medical history of anemia, chronic kidney disease, type 2 diabetes mellitus, and hypertension, presented to the emergency room with acute onset chorea-hemiballism. Patient reported experiencing abnormal movements for two weeks prior to her ER visit, but otherwise denied prior episodes of movement disorders. On physical examination, patient displayed generalized jerky choreiform movements of upper and lower extremities, face, and neck. Upon admission, patient’s blood glucose level was at 311mg/dL; CT of the head was unremarkable and an EEG revealed no abnormalities. The following day, it was found that her blood glucose levels ranged from 150mg/dL to 309mg/dL during the day, and at night, her glucose levels would consistently drop as low as 40mg/dL. Patient underwent an MRI of the head, which revealed no evidence of an acute infarct. The next day, patient’s chorea had improved substantially, although this improvement is most likely attributed to the haloperidol she received prior to the MRI scan. Given her wildly fluctuating blood glucose levels, there was suspicion the chorea-hemiballism was a result of either hypoglycemia or hyperglycemia; however, in the past, patient was admitted to the ER for severe hypoglycemia on numerous occasions and she did not present with chorea during these episodes. Patient was started on olanzapine 2.5mg at bedtime as an empiric management for chorea.

Discussion: Very few cases have illustrated chorea-hemiballism in diabetic patients, but even fewer have depicted such a condition in individuals with negative imaging and with labile glucose levels. This case suggests a rare but far-reaching effect of uncontrolled blood glucose levels.

Presentation Type

Poster

Share

COinS
 

A Case of Chorea-Hemiballism in the Presence of Labile Glucose Levels

Introduction: Uncontrolled blood glucose is notorious for inflicting multi-organ pathologies. One such pathology, chorea-hemiballism, has been reported in individuals who exhibited either hyperglycemia or hypoglycemia, and although rare, it is debilitating and calls for active management.

Case Description: A 50-year-old female, with a past medical history of anemia, chronic kidney disease, type 2 diabetes mellitus, and hypertension, presented to the emergency room with acute onset chorea-hemiballism. Patient reported experiencing abnormal movements for two weeks prior to her ER visit, but otherwise denied prior episodes of movement disorders. On physical examination, patient displayed generalized jerky choreiform movements of upper and lower extremities, face, and neck. Upon admission, patient’s blood glucose level was at 311mg/dL; CT of the head was unremarkable and an EEG revealed no abnormalities. The following day, it was found that her blood glucose levels ranged from 150mg/dL to 309mg/dL during the day, and at night, her glucose levels would consistently drop as low as 40mg/dL. Patient underwent an MRI of the head, which revealed no evidence of an acute infarct. The next day, patient’s chorea had improved substantially, although this improvement is most likely attributed to the haloperidol she received prior to the MRI scan. Given her wildly fluctuating blood glucose levels, there was suspicion the chorea-hemiballism was a result of either hypoglycemia or hyperglycemia; however, in the past, patient was admitted to the ER for severe hypoglycemia on numerous occasions and she did not present with chorea during these episodes. Patient was started on olanzapine 2.5mg at bedtime as an empiric management for chorea.

Discussion: Very few cases have illustrated chorea-hemiballism in diabetic patients, but even fewer have depicted such a condition in individuals with negative imaging and with labile glucose levels. This case suggests a rare but far-reaching effect of uncontrolled blood glucose levels.

 

To view the content in your browser, please download Adobe Reader or, alternately,
you may Download the file to your hard drive.

NOTE: The latest versions of Adobe Reader do not support viewing PDF files within Firefox on Mac OS and if you are using a modern (Intel) Mac, there is no official plugin for viewing PDF files within the browser window.