The central nervous system's (CNS) dopaminergic system dysfunction has been linked to neurological illnesses like schizophrenia and Parkinson's disease. As a result, sensitive and selective detection of dopamine is critical for the early diagnosis of illnesses associated with aberrant dopamine levels. In this research, we have investigated the performance of electrochemical screen-printed sensors for different concentrations of dopamine detection using graphene-based conductive PEDOT: PSS(G-PEDOT: PSS) and Polyaniline(GPANI) inks on the working electrode and compared the sensitivity. SEM characterization technique has been performed to visualize the microstructures of the proposed inks. We have investigated cyclic voltammetry (CV) electrochemical techniques with ferri/ferrocyanide redox couple to assess the efficiency of the designed electrodes in detecting dopamine. GPANI ink has shown to have better LOD and stability to detect dopamine with screen-printed electrodes. Further, we have also studied electrochemical analysis for the selective detection of dopamine without the interference of Ascorbic Acid (AA).
Ghosh, D, Rahman, MA, Ashraf, A, & Islam, N. "Graphene-Conductive Polymer-Based Electrochemical Sensor for Dopamine Detection." Proceedings of the ASME 2022 International Mechanical Engineering Congress and Exposition. Volume 9: Mechanics of Solids, Structures, and Fluids; Micro- and Nano-Systems Engineering and Packaging; Safety Engineering, Risk, and Reliability Analysis; Research Posters. Columbus, Ohio, USA. October 30–November 3, 2022. V009T13A014. ASME. https://doi.org/10.1115/IMECE2022-96193
Proceedings of the ASME 2022 International Mechanical Engineering Congress and Exposition
Copyright © 2022 by ASME. Original published version available athttps://doi.org/10.1115/IMECE2022-96193