Document Type
Article
Publication Date
8-13-2013
Abstract
Men undergo gradual bone loss with aging, resulting in fragile bones. It is estimated that one in five men will suffer an osteoporotic fracture during their lifetime. The prognosis for men after a hip fracture is very grim. A major cause is reduction of free testosterone. Many other factors result in secondary osteoporosis, including treatment for other diseases such as cancer and diabetes. Patients should be screened not only for bone density but also assessed for their nutritional status, physical activity, and drug intake. Therapy should be chosen based on the type of osteoporosis. Available therapies include testosterone replacement, bisphosphonates, and nutritional supplementation with calcium, vitamin D, fatty acids, and isoflavones, as well as certain specific antibodies, like denosumab and odanacatib, and inhibitors of certain proteins.
Recommended Citation
Banu J. (2013). Causes, consequences, and treatment of osteoporosis in men. Drug design, development and therapy, 7, 849–860. https://doi.org/10.2147/DDDT.S46101
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Publication Title
Drug design, development and therapy
DOI
10.2147/DDDT.S46101
Comments
© 2013 Banu, publisher and licensee Dove Medical Press Ltd.