Accessing Reactive Metal Hydrides Through Designed Heterometallic Bridges

Authors

Fernando Gonzalez, The University of Texas Rio Grande Valley
Edgardo De Leon, The University of Texas Rio Grande Valley
Manar M. Shoshani, The University of Texas Rio Grande Valley

Document Type

Article

Publication Date

2-2024

Abstract

A methodology to access reactive hydride moieties is highly desirable, yet limited. Multimetallic hydride fragments are notable for their heightened reactivity and catalysis, but deliberate access to these species is lacking. In this highlight, we discuss recent developments by our group in the design of a new heterometallic complex that invokes an architecture designed to provide modular access to reactive hydride moieties by leveraging metal hydrides in combination with pendent donors to a model heterotrimetallic Ni–(Al–H)2 complex. An amplification of insertion-based reactivity has been examined in the hydrofunctionalization of quinolines, and our complex substantially outperformed the parent aluminum hydride LAlH (L = ligand). A potential rationale for the dramatically increased reactivity, and a further examination of these motifs and methodology in catalysis are also discussed.

Comments

Original published version available at https://doi.org/10.1055/a-2264-9040

Recommended Citation

Gonzalez, Fernando, Edgardo De Leon, and Manar M. Shoshani. "Accessing Reactive Metal Hydrides through Designed Heterometallic Bridges." Synlett 35, no. 18 (2024): 2058-2062. https://doi.org/10.1055/a-2264-9040

Publication Title

Synlett

DOI

10.1055/a-2264-9040