Theses and Dissertations - UTB/UTPA
Date of Award
2002
Document Type
Thesis
Degree Name
Master of Science (MS)
Department
Biology
First Advisor
Dr. K. Daniel Murray
Second Advisor
Dr. Scott Gunn
Third Advisor
Dr. Hassan Ahmad
Abstract
Two genes involved in the metabolism of ppGpp are relA and spoT . A relX mutant has altered ppGpp levels, so relX may be a regulator of the RelA or SpoT enzymes. The growth of the relX mutant has been reported to be both temperature and leucine sensitive. It was discovered in this work that this relX mutant is not temperature sensitive, however it is leucine sensitive. The original goal was to study effects of the relX gene on ppGpp metabolism. During the process of mapping the relX gene, it was discovered that the leucine sensitivity was caused by some other genetic locus. This locus was mapped and identified as either ilvB or ilvN , both of which are genes involved in amino acid biosynthesis.
Granting Institution
University of Texas-Pan American
Comments
Copyright 2002 Roxanne Enid Garza. All Rights Reserved.
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