Document Type

Article

Publication Date

2-19-2019

Abstract

This work addresses a systematic study for the process development and optimization of poly(d,l-lactic acid) (PDLLA) submicrometer fibers utilizing the centrifugal spinning technique known as Forcespinning. This study analyzes the effect of polymer concentration (8, 10, and 12 wt %) and angular speed on the fiber morphology, diameter distribution, and fiber yield. The increase in polymer concentration and angular speed favored the formation of continuous and homogeneous submicrometer fibers with an absence of bead formation and higher output. The optimal conditions were established considering the morphological characteristics that exhibit a greater surface area (homogeneous and submicrometer fibers); and they were achieved at a polymer concentration of 10 wt % at an angular speed ranging from 8000 to 10 000 rpm. Optimization of PDLLA submicrometer fiber fabrication lays the groundwork for scaling up the process and serves as a platform to further develop promising applications of PDLLA nonwoven mats, particularly in the biomedical area such as in scaffolds for tissue engineering.

Comments

© 2019 Wiley Periodicals, Inc. J. Appl. Polym. Sci. 2019, 136, 47643.

https://onlinelibrary.wiley.com/share/RUVI3WDNAK93K3H7YPSM?target=10.1002/app.47643

Publication Title

Journal of Applied Polymer Science

DOI

10.1002/app.47643

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