Cell proliferative properties of Forcespinning® nopal composite nanofibers

Authors

Cristobal Rodriguez, The University of Texas Rio Grande Valley
Victoria I. Padilla, The University of Texas Rio Grande Valley
Karen Lozano, The University of Texas Rio Grande ValleyFollow
Fariha Ahmad, The University of Texas Rio Grande Valley
Alexa Villarreal, The University of Texas Rio Grande Valley
Andrew McDonald, The University of Texas Rio Grande Valley
Luis A. Materon, The University of Texas Rio Grande Valley
Robert Gilkerson, The University of Texas Rio Grande ValleyFollow

Document Type

Article

Publication Date

1-2022

Abstract

In this study, Forcespinning® was used to produce nanofibers composed of Opuntia cochenillifera, “nopal,” mucilage (N) extract, chitosan (CH), and pullulan (PL) (N/CH/PL). These nopal-incorporating nanofibers were examined for their ability to sustain adhesion and proliferation of mouse embryonic fibroblast (NIH 3T3) cells. After a 6-day incubation period, N/CH/PL nanofibers displayed robust cell proliferation, with continued cell growth after an extended incubation period of 14 days. These results demonstrate that natural bioactive compounds can be combined with biodegradable polymers to provide an enhanced environment for cell growth, suggesting potential natural active ingredients as alternatives in wound dressings.

Comments

© The Author(s) 2021.

Recommended Citation

Rodriguez, Cristobal, Victoria Padilla, Karen Lozano, Fariha Ahmad, Alejandra Chapa, Alexa Villarreal, Andrew McDonald, Luis Materon, and Robert Gilkerson. "Cell proliferative properties of Forcespinning® nopal composite nanofibers." Journal of Bioactive and Compatible Polymers 37, no. 1 (2022): 28-37. https://doi.org/10.1177/08839115211060404

Publication Title

Journal of Bioactive and Compatible Polymers

DOI

10.1177/08839115211060404