Harnessing the Potential of Fibrous Polyester Composites Meant for Bioactive Medical Devices

Authors

Graciela Morales
Heriberto Rodríguez-Tobías
Victoria Padilla-Gainza, The University of Texas Rio Grande ValleyFollow
Karen Lozano, The University of Texas Rio Grande ValleyFollow
Daniel Grande

Document Type

Book Chapter

Publication Date

2023

Abstract

Fibrous-based composite polyester mats have gained importance in the biomedical area due to their morphological characteristics and mechanical performance. These materials can be modified by incorporating different inorganic micro- or nano-particles, thus leading to promising potential applications as medical devices with antimicrobial and/or bioactive properties. In this regard, this chapter reports a compilation of different studies related to the development of sub-micron fibers based on two important polyesters for biomedical use, namely poly(3-hydroxybutyrate) and poly(lactic acid). Studies focus on fibers developed through hydrodynamic techniques, namely electrospinning, electrospraying, and centrifugal spinning. The incorporation of zinc oxide or hydroxyapatite on the polyester-based fibers results in materials that inhibit bacterial growth or induce bone cell proliferation. Studies have reported on the effect of the fabrication method as well as the concentration of nanoparticles on the antimicrobial effectiveness against bacteria such as Escherichia coli and Staphylococcus aureus. Particularly, the development of polyesters and their corresponding composites have emerged using a novel and scalable technique named Forcespinning^®. These recent studies report on the influence of morphology and chemical nature on cell adhesion and proliferation and more notable on the ability to mass-produce fibrous-based polyester composite systems with practical applications.

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© 2023 The Author(s), under exclusive license to Springer Nature Switzerland AG

Recommended Citation

Morales, G., Rodríguez-Tobías, H., Padilla-Gainza, V., Lozano, K., Grande, D. (2023). Harnessing the Potential of Fibrous Polyester Composites Meant for Bioactive Medical Devices. In: Avalos Belmontes, F., González, F.J., López-Manchado, M.Á. (eds) Green-Based Nanocomposite Materials and Applications. Engineering Materials. Springer, Cham. https://doi.org/10.1007/978-3-031-18428-4_18

Publication Title

Green-Based Nanocomposite Materials and Applications

DOI

10.1007/978-3-031-18428-4_18