Physician Assistant Studies Faculty Publications

Document Type

Article

Publication Date

6-2010

Abstract

La leishmaniosis tegumentaria americana (LTA) como enfermedad endémica crónica continúa afectando a la población del medio rural venezolano, ocasionándole morbilidad y limitaciones laborales. Mediante la descripción de casos clínicos se evaluaron 38 pacientes con LTA que recibieron atención hospitalaria por úlceras leishmánicas en miembros inferiores. De los pacientes descritos 63 % eran niños, 84 % procedía del Estado Miranda, 66 % tenía una lesión ulcerosa única, 45 % recibió cefadroxilo previo al tratamiento antiparasitario específico y el 24 % había recibido inmunoterapia previa para la enfermedad. Treinta y siete pacientes (97 %) recibieron antimoniato de meglumina en series terapéuticas de diez días y uno anfoterecina B, por contraindicación cardiovascular para el uso del antimonial. Todos presentaron re-epitelización adecuada de sus lesiones, por lo que el antimoniato de meglumina demuestra una vez más su utilidad en la terapéutica de esta zoonosis parasitaria.

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American tegumentary leishmaniasis (ATL) endemic chronic disease continues to affect the population of rural Venezuela, causing morbidity and labor constraints. By the description of clinical cases were evaluated 38 patients with ATL who received hospital care for leishmanial ulcers in lower limbs. Sixty-three percent of the patients were children, 84 % came from Miranda state, 66 % had a unique ulcerated lesion, 45 % received cefadroxil prior to parasite specific treatment and 24 % had received immunotherapy for the disease. Thirtyseven patients (97 %) received meglumine antimoniate in series of ten days and one patient received anfotericine B, due to cardiovascular contraindication for the use of the antimonial. All ulcers healed. The antimoniate of meglumine demonstrates once again its usefulness in the treatment of this parasitic zoonosis.

First Page

48

Last Page

52

Publication Title

Boletín Venezolano de Infectología

Included in

Public Health Commons

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