Document Type
Article
Publication Date
2023
Abstract
Introduction: Spinal Cord Injuries (SCI) are catastrophic injury to spinal neurons that cause a tremendous socioeconomic and public health burden on individuals globally. The role of fatty acids in treatment of SCI is not well understood and poorly standardized across treatment provision. This review seeks to explore the role of fatty acids in neurorecovery and propose emerging themes in SCI treatment with fatty acids.
Methods: A PICO was designed and online databases were searched for relevant articles. A total of 55 studies were deemed appropriate for the review and summarized into thematic elements including ) Cellular Transport 2) Neuroprotection 3) SCI Treatment.
Results: Polyunsaturated Fatty Acids (PUFAs) were the primary treatment of interest and demonstrated overall beneficial effect on neuroregeneration and SCI recovery. No consensus was found between selection, dosing, and measurement of SCI treatment outcomes in studies between 1982 and 2023.
Discussion: Publication biases were substantiated in systematic review of studies pertaining to PUFAs and SCI; further research is needed to understand the role of fatty acids and SCI treatment.
Recommended Citation
Dentino, Philippe J., "Fatty Acid therapy and Implications for Spinal Cord Injury Treatment: A Literature Review" (2023). MEDI 9331 Scholarly Activities Clinical Years. 77.
https://scholarworks.utrgv.edu/som9331/77
Academic Level
medical student
Mentor/PI Department
Neuroscience
Included in
Lipids Commons, Nervous System Diseases Commons, Neurosurgery Commons, Physiological Processes Commons