Infant behavioral reactivity predicts change in amygdala volume 12 years later

Authors

Courtney A. Filippi
Jessica F. Sachs
Dominique Phillips
Anderson M. Winkler, The University of Texas Rio Grande ValleyFollow
Andrea L. Gold
Ellen Leibenluft
Daniel S. Pine
Nathan A. Fox

Document Type

Article

Publication Date

4-1-2020

Abstract

The current study examined the link between temperamental reactivity in infancy and amygdala development in middle childhood. A sample (n = 291) of four-month-old infants was assessed for infant temperament, and two groups were identified: those exhibiting negative reactivity (n = 116) and those exhibiting positive reactivity (n = 106). At 10 and 12 years of age structural imaging was completed on a subset of these participants (n = 75). Results indicate that, between 10 and 12 years of age, left amygdala volume increased more slowly in those with negative compared to positive reactive temperament. These results provide novel evidence linking early temperament to distinct patterns of brain development over middle childhood.

Comments

Under a Creative Commons license

Recommended Citation

Filippi, C. A., Sachs, J. F., Phillips, D., Winkler, A., Gold, A. L., Leibenluft, E., ... & Fox, N. A. (2020). Infant behavioral reactivity predicts change in amygdala volume 12 years later. Developmental Cognitive Neuroscience, 42, 100776. https://doi.org/10.1016/j.dcn.2020.100776

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.

First Page

100776

Publication Title

Developmental cognitive neuroscience

DOI

10.1016/j.dcn.2020.100776

Academic Level

faculty

Mentor/PI Department

Office of Human Genetics