School of Medicine Publications and Presentations
Document Type
Article
Publication Date
6-2024
Abstract
In the study of coronary artery disease (CAD), the mechanism of plaque formation and development is still an important subject for investigation. A limitation of current coronary angiography (CAG) is that it can only show static images of the narrowing of arterial channels without identifying the mechanism of the disease or predicting its progression or regression. To address this limitation, the CAG technique has been modified. The new approach emphasizes identifying and analyzing blood flow patterns, employing methodologies akin to those used by hydraulic engineers for fluid or gas movement through domestic or industrial pipes and pumps. With the new technique, various flow patterns and arterial phenomena—such as laminar, turbulent, antegrade, retrograde, and recirculating flow and potentially water hammer shock and vortex formation—are identified, recorded, and classified. These phenomena are then correlated with the presence of lesions at different locations within the coronary vasculature. The formation and growth of these lesions are explained from the perspective of fluid mechanics. As the pathophysiology of CAD and other cardiovascular conditions becomes clearer, new medical, surgical, and interventional treatments could be developed to reverse abnormal coronary flow dynamics and restore laminar flow, leading to improved clinical outcomes.
Recommended Citation
Nguyen, T., Ngo, K., Vu, T. L., Nguyen, H. Q., Pham, D. H., Kodenchery, M., Zuin, M., Rigatelli, G., Nanjundappa, A., & Gibson, M. (2024). Introducing a Novel Innovative Technique for the Recording and Interpretation of Dynamic Coronary Angiography. Diagnostics (Basel, Switzerland), 14(12), 1282. https://doi.org/10.3390/diagnostics14121282
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Publication Title
Diagnostics
DOI
10.3390/diagnostics14121282
Academic Level
resident
Mentor/PI Department
Internal Medicine
Comments
Copyright © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).