School of Medicine Publications and Presentations
Document Type
Response or Comment
Publication Date
7-16-2024
Abstract
Vitamin D is a pleiotropic hormone that regulates calcium and phosphate homeostasis. The roles of vitamin D can be divided into skeletal and nonskeletal. Its skeletal roles include promoting calcium absorption in the intestines, maintaining adequate levels of calcium and phosphate in the bloodstream, and supporting bone mineralization, thus preventing conditions such as rickets and osteoporosis. Nonskeletal roles encompass a range of functions, including immune system modulation, cardiovascular health, and cell growth regulation. Sufficient concentrations of vitamin D in the bloodstream are 20–100 ng/ml in men, women, and children, but individuals with more pigmented skin, live in environments with less sun exposure, or who are older in age are at increased risk of vitamin D deficiency (1). In the past decade, vitamin D has been repeatedly shown to halt tumorigenesis, positively affect T-cell function, improve lung function, and play a role in the pathogenesis of diabetes mellitus. Arsenic has been shown to have harmful consequences on human health, and more individuals are exposed to increasing amounts of arsenic in their environment due to natural sources, such as mineral deposits in water, and unnatural sources, such as pollution. This brief article describes how arsenic might interact with vitamin D.
Recommended Citation
Chittilla, M., Uzoma, C., Brewer, D., & Razzaque, M. S. (2024). Potential association between arsenic and vitamin D. Frontiers in endocrinology, 15, 1430980. https://doi.org/10.3389/fendo.2024.1430980
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Publication Title
Frontiers in endocrinology
DOI
https://doi.org/10.3389/fendo.2024.1430980
Academic Level
faculty
Mentor/PI Department
Medical Education
Comments
Copyright © 2024 Chittilla, Uzoma, Brewer and Razzaque. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.