Radiation Therapy in Metastatic Neuroblastoma

Authors

Meenu Gupta
Anupam Dhasmana, The University of Texas Rio Grande Valley

Document Type

Book

Publication Date

2018

Abstract

Neuroblastoma is the commonest extracranial solid tumor in children, and metastasis at presentation is seen in more than 50% of cases. The role of radiotherapy as a palliative modality in patients with advanced neuroblastoma provides better symptomatic relief. Palliative radiotherapy dose schedules can be given either in single hypofractionation from 4 to 8 Gy or fractionated radiotherapy that can range from 21 to 30.6 Gy. Doseresponse relationship trend has been reported in the palliative setting of bone metastasis. Because of the proximity of tumor to critical organs, serious adverse effects can be avoided with conformal techniques. Although currently there is limited data available, new treatments with particle therapies are undergoing clinical evaluation and may offer new hope for good quality of life in these patients.

Comments

© 2016 The Author(s). Licensee InTech.

ISBN: 978-1-83880-284-4

Recommended Citation

Gupta, M., & Dhasmana, A. (2018). Radiation Therapy in Metastatic Neuroblastoma. In Nuclear Medicine Physics (pp. 7–21). https://doi.org/10.5772/intechopen.80892

First Page

7

Last Page

21

Publication Title

Nuclear Medicine Physics

DOI

10.5772/intechopen.80892

Academic Level

faculty

Mentor/PI Department

Immunology and Microbiology