School of Medicine Publications and Presentations
Document Type
Article
Publication Date
5-2025
Abstract
The Alzheimer's Disease Research Centers (ADRCs) consortium represents a critical locus of research on Alzheimer's disease and related disorders (ADRD) prevention, diagnosis, and intervention. Through the National Alzheimer's Coordinating Center's (NACC) standardized protocol, the Uniform Data Set (UDS), ADRCs have collected rich, harmonizable clinical and cognitive data. However, the collection of social data has been sparse and Center specific, constraining ADRD science that addresses research priorities on social determinants of health (SDOH) and health equity. Capitalizing on the transition to a revised UDS version 4, an interdisciplinary committee representing 10 ADRCs reviewed the literature and instrumentation, ultimately creating a brief module covering multiple domains and levels of exposure required for mechanistic studies of SDOH and brain health. This article offers rationale, empirical support, and guidance for using the selected constructs: transportation security, financial security, social connectedness, health care experiences, and discrimination, as well as recommendations for next steps that each ADRC can take to maximize local and field-level progress.
Recommended Citation
Zuelsdorff, M., Abner, E. L., Balls‐Berry, J. E., Jicha, G. A., Lanata, S., Maestre, G. E., ... & Barnes, L. L. (2025). Introducing social determinants of health to the Alzheimer's Disease Research Center network: Development and implementation in the Uniform Data Set. Alzheimer's & Dementia, 21(5), e70279. https://doi.org/10.1002/alz.70279
Creative Commons License
This work is licensed under a Creative Commons Attribution 4.0 International License.
Publication Title
Alzheimer's & Dementia
DOI
10.1002/alz.70279
Academic Level
faculty
Mentor/PI Department
Neuroscience
Comments
© 2025 The Author(s). Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association.
This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.