School of Medicine Publications
Document Type
Article
Publication Date
4-17-2024
Abstract
The limitations of conventional therapeutic treatments prevailed in the development of nanotechnology-based medical formulations, termed nanomedicine. Nanomedicine is an advanced medicine that often consists of therapeutic agent(s) embedded in biodegradable or biocompatible nanomaterial-based formulations. Among nanomedicine approaches, tablet (oral) nanomedicine is still under development. In tabletized nanomedicine, the dynamic interplay between nanoformulations and the intricate milieu of the gastrointestinal tract simulates a pivotal role, particularly accentuating the influence exerted upon the luminal, mucosal, and epithelial cells. In this work, we document the perspectives and opportunities of nanoformulations toward the development of tabletized nanomedicine. This review also unveils the notion of integrating nanomedicine within a tablet formulation, which facilitates the controlled release of drugs, biomolecules, and agent(s) from the formulation to achieve a better therapeutic response. Finally, an attempt was made to explore current trends in nanomedicine technology such as bacteriophage, probiotic, and oligonucleotide tabletized nanomedicine and the combination of nanomedicine with imaging agents, i.e., nanotheranostics.
Recommended Citation
Tiwari, R., Kolli, M., Chauhan, S., & Yallapu, M. M. (2024). Tabletized nanomedicine: From the current scenario to developing future medicine. ACS nano, 18(18), 11503-11524. https://doi.org/10.1021/acsnano.4c00014
Publication Title
ACS Nano Medicine
DOI
10.1021/acsnano.4c00014
Academic Level
faculty
Mentor/PI Department
Immunology and Microbiology
