Granulomatosis With Polyangiitis in a Pediatric Male

Authors

Florentino Saenz Rios, University of Texas Medical Branch
Sandhya Devaraj
Giri Movva, The University of Texas Rio Grande Valley
Hari Movva
Quan D. Nguyen

Document Type

Article

Publication Date

12-13-2020

Abstract

Significant eosinophilia is a prominent feature in Churg-Strauss syndrome but has not been described in granulomatosis with polyangiitis (GPA) in a pediatric patient. We present a biopsy case that confirmed granulomatosis with polyangiitis with significant eosinophilia > 30% on the initial presentation. Etiologies that could account for eosinophilia were excluded during workup. The patient's presentation of pulmonary alveolar hemorrhage, conjunctivitis arthritis, high-titer cytoplasmic antineutrophil, PR3-ANCA antibodies, and cytoplasmic antibodies (cANCA) was consistent with a clinical picture of atypical GPA in a pediatric patient. This case presents a rare opportunity not only due to GPA’s low incidence in the pediatric population but due to the unusual nature of significant eosinophilia in GPA.

Comments

© Copyright 2020 Saenz Rios et al.

Recommended Citation

Saenz Rios F, Devaraj S, Movva G, et al. (December 13, 2020) Granulomatosis With Polyangiitis in a Pediatric Male. Cureus 12(12): e12055. DOI:10.7759/cureus.12055

Publication Title

Cureus

DOI

10.7759/cureus.12055

Academic Level

medical student

Mentor/PI Department

Surgery