School of Medicine Publications and Presentations
Document Type
Article
Publication Date
6-2015
Abstract
Purpose
Examine whether maternal asthma contributes to racial/ethnic differences in obstetric and neonatal complications.
Methods
Data on White (n=110,603), Black (n=50,284) and Hispanic (n=38,831) singleton deliveries came from the Consortium on Safe Labor. Multi-level logistic regression models, with an interaction term for asthma and race/ethnicity, estimated within-group adjusted odds ratios (aOR) for gestational diabetes, gestational hypertension, preeclampsia, placental abruption, premature rupture of membranes, preterm delivery, maternal hemorrhage, NICU admissions, small for gestational age (SGA), apnea, respiratory distress syndrome, transient tachypnea of the newborn, anemia and hyperbilirubinemia after adjustment for clinical and demographic confounders. Non-asthmatics of the same racial/ethnic group were the reference group.
Results
Compared to non-asthmatics, White asthmatics had increased odds of preeclampsia (aOR 1.28; 95% CI: 1.15–1.43) and maternal hemorrhage (1.14; 1.04–1.23). White and Hispanic infants were more likely to have NICU admissions (1.19; 1.11–1.28; 1.16; 1.02–1.32, respectively) and be SGA (1.11; 1.02–1.20; 1.26; 1.10–1.44, respectively) and Hispanic infants were more likely to have apnea (1.32; 1.02–1.69).
Conclusions
Maternal asthma did not impact most obstetric and neonatal complication risks within racial/ethnic groups. Despite their increased risk for both asthma and many complications, our findings for Black women were null. Asthma did not contribute to racial/ethnic disparities in complications.
Recommended Citation
Flores, K. F., Robledo, C. A., Hwang, B. S., Leishear, K., Laughon Grantz, K., & Mendola, P. (2015). Does maternal asthma contribute to racial/ethnic disparities in obstetrical and neonatal complications?. Annals of epidemiology, 25(6), 392–397.e1. https://doi.org/10.1016/j.annepidem.2015.01.011
Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial-No Derivative Works 4.0 International License.
Publication Title
Annals of Epidemiology
DOI
10.1016/j.annepidem.2015.01.011
Academic Level
faculty
Mentor/PI Department
Population Health and Biostatistics
Comments
© 2015 Published by Elsevier Inc. Original published version available at https://dx.doi.org/10.1016%2Fj.annepidem.2015.01.011