Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis

Authors

Justin Wendel, The University of Texas Rio Grande Valley
A. Verma
Vijian Dhevan
Subhash C. Chauhan, The University of Texas Rio Grande ValleyFollow
Manish Tripathi, The University of Texas Rio Grande Valley

Document Type

Article

Publication Date

7-12-2021

Abstract

Stress management is becoming very important part of cancer patient care. Chronic stressors lead to boost tumorigenesis and promote cancer development, recurrence, and drug resistant leading to poor health outcomes. The Hypothalamic-Pituitary-Adrenal (HPA) axis, which is activated by stress, also regulates Hypothalamic-Pituitary-Thyroid (HPT) axis. Stress related changes in immune function and inflammatory response also leads to reduced immune surveillance resulting in tumorigenesis. This article explores the hormonal axis impacted by stress and how chronic stress can lead to poor outcome of a cancer patient.

Comments

Copyright Tripathi MK

Recommended Citation

Wendel, J., Verma, A., Dhevan, V., Chauhan, S. C., & Tripathi, M. K. (2021). Stress and Molecular Drivers for Cancer Progression: A Longstanding Hypothesis. Biomedical journal of scientific & technical research, 37(1), 29134–29138. https://doi.org/10.26717/bjstr.2021.37.005953

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Publication Title

Biomed J Sci & Tech Res

DOI

10.26717/BJSTR.2021.37.005953

Academic Level

faculty

Mentor/PI Department

Immunology and Microbiology