School of Medicine Publications and Presentations

Document Type

Conference Proceeding

Publication Date

3-2020

Abstract

Background

Takotsubo cardiomyopathy (TSC) can be preceded by emotional, physical, or no identifiable trigger. Despite being a transient condition, it is associated with a substantial risk for in-hospital adverse events. The clinical features and the short-term outcomes of TSC in South Texas Hispanics (STH) are unknown.

Methods

We identified patients with the diagnosis of TSC at an academic institution from 2005-2017. Patients who did not have coronary angiography were excluded. Demographics, presenting symptoms, triggers, left ventricular characteristics and outcomes were expressed as percentages. Continuous variables were expressed as means.

Results

Of 41 patients with TSC, the diagnosis was confirmed in 38, of which 27 (71.1%) were Hispanics. In this group, the mean (±SD) age was 69±11.5 years; 92.6% were women. Comorbidities included: hypertension (70%), obesity (47%), and diabetes (30%). The most common presenting symptoms were chest pain (66.7%) and dyspnea (48.2%). Physical, emotional, and no specific triggers were identified in 37.4%, 33.3%, and 29.6% of the patients, respectively. Apical and mid-ventricular TSC were identified in 95% and 5% of the patients, respectively. The mean left ventricular ejection fraction was 35.9±10.3%. Cardiogenic shock and respiratory failure occurred in 37% and 25.9% of the patients, respectively. There were no in-hospital deaths in the entire cohort.

Conclusion

The clinical features and short-term outcomes of TSC in STH are similar to those found in recently published data. Emotional triggers are not as common as initially thought. The rate of severe in-hospital complications occurred in at least one-third of the patients, but there were no deaths.

Comments

© 2020 American College of Cardiology Foundation. Original published version available https://doi.org/10.1016/S0735-1097(20)31694-6

Publication Title

Journal of the American College of Cardiology

DOI

10.1016/S0735-1097(20)31694-6

Academic Level

faculty

Mentor/PI Department

Medical Education

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