School of Medicine Publications and Presentations
Kaposi sarcoma incidence in females is nearly four-fold higher in the Lower Rio Grande Valley compared to the Texas average
The Lower Rio Grande Valley (LRGV) is located on U.S.-Mexican border with a population that is 90% Hispanic . Comprised of Hidalgo, Cameron, Starr and Willacy counties, this region has the highest poverty rate and one of the highest incidences of Type 2 diabetes in the United States , , . Previous studies demonstrated a high prevalence of Human Herpes Virus 8 (HHV8) in the LRGV , , . HHV8 infection has been causally linked to Kaposi Sarcoma (KS) . Here, we retrospectively examine the incidence of KS in the LRGV in a set of HIV-negative Hispanic patients. Strikingly, the incidence of KS was higher in LRGV women compared to the Texas state average (nearly four-fold higher in McAllen-Edinburg-Pharr Metro Statistical Area). This unique profile aligns with the increased HHV8 prevalence in the LRGV, suggesting that HHV8 contributes to a high incidence of HIV-negative KS on the U.S.–Mexican border in Texas.
Innis-Whitehouse, W., Wang, X., Restrepo, N., Salas, C., Moreno, K., Restrepo, A., & Keniry, M. (2018). Kaposi sarcoma incidence in females is nearly four-fold higher in the Lower Rio Grande Valley compared to the Texas average. Cancer treatment and research communications, 16, 45–52. https://doi.org/10.1016/j.ctarc.2018.06.003
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Cancer treatment and research communications
Original published version available at https://doi.org/10.1016/j.ctarc.2018.06.003