Posters

Presenting Author

Tunde Olaniyan

Presentation Type

Poster

Discipline Track

Clinical Science

Abstract Type

Research/Clinical

Abstract

Background: Traffic Compliance and Enforcement (TRACE) Corps members in Nigeria are occupationally exposed to lots of environmental pollutants due to essential services that they render in the transport industry. Exposure to environmental pollutants has been shown to contribute to the pathogenesis and progression of cardiovascular diseases (CVD). Information about biochemical end points of CVD in Traffic Compliance and Enforcement (TRACE) Corps members who are occupationally exposed to environmental pollutants is lacking. This study therefore investigated the effects of these environmental pollutants on some indices of CVD.

Methods: Before enrollment in the study, all subjects, including controls, were informed about the objectives and requirements of the study, as well as the risks and discomfort that might be involved in participating in the study. After this exercise, a total of 234 subjects consented to participate in the study. TRACE (n=195) in various zones in Ogun State. Staff and students at Federal University of Agriculture, Abeokuta (FUNAAB) served as control subjects (n=39). A careful history of their dietary habits and job experience, as well as a detailed history of their occupational habit, was taken. Anthropometric and clinical parameters were assessed using standard methods while biochemical indices of CVD were determined spectrophotometrically using commercial diagnostic kits. One-way analysis of variance (ANOVA) followed by Duncan test was used to analyze the results with p<0.05 considered significant. The relationships between plasma lipids and the anthropometric parameters were also analyzed using Pearson correlations.

Results: Results showed that the systolic blood pressure in both male and female TRACE subjects were significantly higher than the control subjects. The diastolic blood pressure remained the same in both the control and TRACE subjects. The pulse in the TRACE male subject was significantly lower than the control subject. The body mass index (BMI), waist circumference and hip circumference of the TRACE female were significantly higher than the control subjects. The umbilical cord circumference of the TRACE male and female subjects were significantly higher than their control counterpart. Plasma Cholesterol in TRACE male was higher than the control male while the plasma cholesterol was lower in TRACE female compared to the control female. Plasma triacylglycerol and phospholipid remain the same in all subjects. HDL cholesterol in the TRACE subjects were 65% and 71% of the control male and control female respectively. Plasma arylesterase in TRACE male and female subjects were both 1.39 times lower than their control counterparts. There was also a significant positive correlation between the plasma cholesterol and weight (r = 0.130; p = 0.047), plasma cholesterol and BMI (r = 0.157; p = 0.021), Plasma triacylglycerol and Pulse (r = 0.130; p = 0.048). The average traffic density was 37 vehicles/min in the sampled TRACE zones.

Conclusion: Findings such as increase in systolic blood pressure, anthropometric parameters and lower HDL cholesterol, plasma arylesterase in the TRACE subjects compared to the control from this study indicates that environmental pollutant exposure may disrupt lipid homeostasis and predisposes the TRACE subjects to development of CVD.

Academic/Professional Position

Graduate Student

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Impacts of Work Environment on Health Status of Traffic Compliance and Enforcement Corps Members in Ogun State. Nigeria

Background: Traffic Compliance and Enforcement (TRACE) Corps members in Nigeria are occupationally exposed to lots of environmental pollutants due to essential services that they render in the transport industry. Exposure to environmental pollutants has been shown to contribute to the pathogenesis and progression of cardiovascular diseases (CVD). Information about biochemical end points of CVD in Traffic Compliance and Enforcement (TRACE) Corps members who are occupationally exposed to environmental pollutants is lacking. This study therefore investigated the effects of these environmental pollutants on some indices of CVD.

Methods: Before enrollment in the study, all subjects, including controls, were informed about the objectives and requirements of the study, as well as the risks and discomfort that might be involved in participating in the study. After this exercise, a total of 234 subjects consented to participate in the study. TRACE (n=195) in various zones in Ogun State. Staff and students at Federal University of Agriculture, Abeokuta (FUNAAB) served as control subjects (n=39). A careful history of their dietary habits and job experience, as well as a detailed history of their occupational habit, was taken. Anthropometric and clinical parameters were assessed using standard methods while biochemical indices of CVD were determined spectrophotometrically using commercial diagnostic kits. One-way analysis of variance (ANOVA) followed by Duncan test was used to analyze the results with p<0.05 considered significant. The relationships between plasma lipids and the anthropometric parameters were also analyzed using Pearson correlations.

Results: Results showed that the systolic blood pressure in both male and female TRACE subjects were significantly higher than the control subjects. The diastolic blood pressure remained the same in both the control and TRACE subjects. The pulse in the TRACE male subject was significantly lower than the control subject. The body mass index (BMI), waist circumference and hip circumference of the TRACE female were significantly higher than the control subjects. The umbilical cord circumference of the TRACE male and female subjects were significantly higher than their control counterpart. Plasma Cholesterol in TRACE male was higher than the control male while the plasma cholesterol was lower in TRACE female compared to the control female. Plasma triacylglycerol and phospholipid remain the same in all subjects. HDL cholesterol in the TRACE subjects were 65% and 71% of the control male and control female respectively. Plasma arylesterase in TRACE male and female subjects were both 1.39 times lower than their control counterparts. There was also a significant positive correlation between the plasma cholesterol and weight (r = 0.130; p = 0.047), plasma cholesterol and BMI (r = 0.157; p = 0.021), Plasma triacylglycerol and Pulse (r = 0.130; p = 0.048). The average traffic density was 37 vehicles/min in the sampled TRACE zones.

Conclusion: Findings such as increase in systolic blood pressure, anthropometric parameters and lower HDL cholesterol, plasma arylesterase in the TRACE subjects compared to the control from this study indicates that environmental pollutant exposure may disrupt lipid homeostasis and predisposes the TRACE subjects to development of CVD.

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